PCRYJ

I recently encountered a VERY troublesome issue with my disk drive where it is unable to run a CD or DVD. The situation is that I put a disk into the drive, close the drive, it reads the disk but nothing happens. Nothing pops up. Everytime I put a disk into my disk drive, my computer semi-freezes. I am able to open folders, but If I try to connect to the Internet or I am currently trying to go to my homepage and I put a disk into the drive, it will stop UNTIL I take the disk out of the drive. Right when I open my disk drive, my computer goes back to normal. Another thing, if I have a disk in my disk drive when I'm booting up my computer, my computer will stop at a black screen right before the Windows Vista Welcome Screen. Again, until I open my disk drive, my computer will not load to my desktop.

...So I bought a new disk drive thinking it's the drive's fault. The new disk drive acts the same exact way as the old one. So now I know it is some other hardware or software piece that is causing this problem.
---If anyone knows how I can fix this problem, or if anyone has any helpful suggestions or solutions, it would be greatly appreciated!

My Computer Specifications:

-Intel Core 2 Duo E6700
-Nvidia 8800GTX
-ASUS P5N32-SLI SE Deluxe Gaming Motherboard
-700W FSP Group PSU