Laptops are typically slower due to lower power consumption devices inside. Laptop drives are typically slower too because they are limited to how fast they can go. DVDs are limited to 8x(at least all I've seen), CDs around 24x, and harddrives by around 7200RPMs.
Storage is less, harddrives are usally 100G max. I don't really look for these drives so there might be larger ones around now...
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Desktop * Athlon X2 4200 | 2G RAM | 160G HD | 7600GT
Laptop1 * C2D T5550 | 3G RAM | 120G HD | Intel x3100
Laptop2 * C2D T5250 | 2G RAM | 160G HD | Intel x3100
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