It seems we have a weekly poll on the same subject. One of these there may be a sticky on antivirus programs like the ways of prevention covered in
Basic Malware Prevention
McAFee had it's one time chance some years back and never again was the initial verdict for a good numbers of reasons. The free version of AVG provided for home use by Grisoft on the other hand has even worked better at actually catching and pointing a variety of "bugs"(trojans, trojan downloaders, malwares) then the other antispyware programs shown in the sticky with the exception of Ad-Aware which now sees a 2007 free version bu Lavasoft. Ad-Aware likes to catch browser hijackers.