Doesn't sound like a computer problem. Of course there are always files that don't like to intertwine. I've seen this happen on another comp where it wouldn't install without a 98SE cd. Of course this isn't your problem, but creative doesn't make the best software and it seems the software doesn't like anything but itself if you know what i mean. I would run a check disk to see if that might clear up some problems, it's worked for me. If not contact creative.
(actually don't they are terrible to get on the phone). Just put in the error number and message you get and google search it, someone way smarter than me probably figured it out. and do what praetor said.