Originally Posted by Timo

Well to actually give enough information to those 4 GPU's you will need a monster Quad-Core where all cores get used... Find me a game that uses 4 cores! :p

Tri-SLI would be more then enough right now. Three 9800GTX's in Tri-SLI on a 790i from eVGA with a Q9770 overclocked to... 5Ghz...