I know the 2 medium range Acers I had failed fairly quickly (GPU failure and Motherboard fried). Higher models might be better, but personally I would avoid them.
This is funny to me since the worst car I have ever owned was a 1984 Toyota Camry and one of the best I've ever owned is a 2001 Kia Rio (based on reliability and how many times it needed to be towed or put in the shop). I hated the Camry so much that the last time it left me stranded by the side of the highway I refused to fix it again and gave it away. Still have the Rio, in the 12 years we've owned it, it has only been in the shop once (other than for oil changes and regular maintenance).... To me, and Acer is like a Kia whereas an ASUS is like a Toyota. Don't confuse the two just because their names sound alike. ...