Lost you rock bro, I thought guys like John or I were the older group but you make me feel younger

. I don't no exactly why you need so many usb ports but you do. If you were in the computer field you will be just fine, sounds to me as if you just want some advice on the new stuff. And it seems everytime the wind blows something new is out. I'll give you my opinion and it's just that mine.
Case Corsair 400R (so many to choose from, but I like this one.) $90
CPU i5 3570K $190 @ micro center or $229 other places
CPU cooler CM212 is a great buy @ $30
High end coolers like a Noctua will run around $80-100
Then there's always water looped systems, but this can get costly and I don't think it's necessary unless you plan on getting into big OC.
Mobo Gigabyte UD3H or UD5H for more usb ports which sounds like this is what you want. If you don't need multiple PCi slots and some extra features you can get a more economical DS3H version. $110-190
8GB min. or you can run 16GB just because you can

. Your choice, maybe corsair or Gskill $60-100
GPU this is a hard choice ,strickly on my preference GTX 670 FTW version, but if you need multiple monitors more ram go with a amd 7970. If you don't want to spend 400+ for a card you can go with a amd 7850/7870 or a GTX 570 or even a GTX 480 at a great price. So many choice and most will not be a bad decision. You need to decide what you want to spend and get that card in the budget look at both amd/nvidia with an open mind. You will have fan boys on each side. I said the 670 only cause I've been running a amd and wanted to try something different. Side note I've never had driver issues with mine.
$200-400
Blue Ray or DVD LG, Samsung, Asus $20-80
PSU Corsair very popular along with pc cooling although not as popular, I've had good luck with the price conscience OCZ 700 modular. $50-80
SSD if you want a quick boot up or load games on this drive, it might make it a few milliseconds quicker. I've not jumped on this band wagon nor have I ever tried them so my opinion is one sided. Someone with more knowledge can help you here better.
HDD Seatgate Barracuda or WD Black Caviar 1TB 7200RPM 64MB Cache 6.0 GB/S or bigger depending on how much storage you need. I prefer WD myself.
OS Whatever you decide, Win 7 professional is a good choice.
Hope my .02 helped you out. But then again it's only .02..... :good: