Can you make 2 hard drives work as one?

ADE

banned
OK, here's my thought. If you have 2 or more HDD's it can get a little messy at times. But for example, say you had to partitions on one HDD. Its like have 2 HDD's on one HDD. My question is can you make multiple HDD's work like partitions from one HDD? That way it's just like one BIG drive. Is that possible?
And to bring up something rather opposite, If you have, oh say, 4 people that share 1 computer, is it possible to have 4 HDD's and everyone has there own HDD but in order to go on that HDD you have log into your account. So its like having 4 computers, only in one so that each person gets there own HDD and no one else can use it.
 
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