The older Windsor/Brisbane AM2 processors, if it had a odd CPU X would drop the memory back. Say with a X2 6000, stock it would run the memory at around 375/750 instead of 400/800. But it was fixed on the Phenom, doesnt matter what the CPU X is set at. If you use the CPU X, it doesnt effect the MHZ or Timing. If you overclocking using the Bus and have the memory voltage and timing set to Auto, it could set the timing back.