We need much more information that this. What OS are you running? When does this pop up? Could you post a screen shot? Maybe download Hijackthis and post the log here.
Do you use any visual studio sofware? I think if you are used and for this reason it occured. i used and the same problem i faced. You can use NOD32 for removing your registry.
If so In Internet Explorer go to "Tools", "Internet Options", "Advanced" and scroll down to "Disable Script Debugging" and put a tick next to it.
Restart IE.
To find Visual Studio:
Start menu
Control panel
Install/Unistall programs
check for the Visual studio (probably in the end of the list)
try to do an repair
This [pop up] looks to be part of: Microsoft Script Editor. I have been looking for a way to turn it off. The ,pop ups , show up while I'm on a forum, saying: runtime error, do you want to debug?.
I was able to turn of the De Buging pop ups. When I came back to post how I had done this I found that TFT, in the UK,had posted on this thread long time back how to do it.
Thanks! Guess I wasn't paying attention. Richard