Is this MoBo and RAM compatible with eachother?

The standard memory for that model Asus board is DDR2 800. The Patroit memory you picked out is DDR2 667. There you would have lower the fsb if the board does do this automatically. You may want to go with a different brand like Corsair, Kingston, Crucial, Mushkin, or another older named brand however. Patriot and a few others are recent brands to be seen.

According to the product details seen at http://www.asus.com/products4.aspx?l1=3&l2=11&l3=0&model=1295&modelmenu=1 you shouldn't need one right away unless an older bios version is on. Then you would simply download and install the update to see the support added. To see what version is currently on the system and for bios along with other updates go to http://support.asus.com/download/download.aspx?SLanguage=en-us&model=P5B Deluxe
 
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