Of course, you can.
Just follow the steps below:
In fact, almost the temporary files are restored in the C:/Docucments and Settings/Users’ name, you can remove them as follows:
1. Open C: /Documents and Settings/Users’ name/Cookies, delete all the files, because it restores the left index files when visiting websites.
2. In the C: /Documents and Settings/Users’ name/Local Settings/History, delete the files since they belong to history record.
3. In the C: /WINDOWS/Temp, remove all these temporary files.
4. In the C:/Documents and Settings/Users’ name/Local Settings/Temp, remove such user’s temporary visiting files.
5. Open C:/Documents and Settings/Users’ name/Local Settings/Temporary Internet Files, delete all the page files.
6. In the C:/Documents and Settings/Users’ name/Recent folder, you can delete all these shortcuts of recent browsed files.
7. In the C: /WINDOWS/Software Distribution/download, get rid of all the temporary files when downloading.
8. In the C: /WINDOWS/Driver Cache/386, delete all the compressed files.
And then, you can clean regsitry. Well I turn to a third-party tool rather than do that by myself.
Go to this article, find more methods:
http://ezinearticles.com/?Fix-Slow-PC---How-to-Speed-Up-PC-As-Fast-As-Possible&id=3704332