If you want to be able to record the differences, either download PCMark (similar to 3DMark, but benches the whole system), or an even better tool would be Sandra Lite 2007, which has specific memory bandwidth tests.
Core 2's hide high latencies fairly well and on top of that reducing them by 1 doesn't do a whole lot anyway, going from 6-6-6 to 4-4-4 should be a noticable difference but still small.
The timings are how many clock cycles the controller has to wait for the memory to do stuff. There is a delay for each operation, CAS and CMD timings are applied to every RAM access which is why they make the biggest difference and many people just kind of forget about the other timings.