is it an ctive keyboard??
Could it be that the key board is from a big company like logitech. If that is the case. it could be that you istald a driver from cd. so the keyboard is running from a not so standard driver. Dos will not see it so you can't work with it.
in safe mode all special drivers are shut down, so your keyboard runs on a standard driver.
try uninstaling your keynorad, and reinstaling it whitout that driver.
But al specials functions like an internet/mail/msn/what ever button won't work
daniel