By default, no, no, and no. But seeing how it has USB, with the correct software I'm sure you could use a keyboard and mouse on it. I actually have PS2(as in keyboard) converter for my Dreamcast so I can use a keyboard with it. However, I know Sega made a keyboard for it...
As for VGA, I know the dreamcast and I beleive Xbox both had VGA output converters, but I don't know right off if the PS2 has one as well.