you will not see much difference in RAM with higher speed. More exact, if you need 2 GB, you will need 2GB weather it is 133MHz or 5GHz.
I would say 12 or 16 GB in dual channel mode would be in the area of what you need. You may get away with less, just depends on what you are doing with your VM.
It does not mean it will not work. It just means that they have not tested it in that board.