While the i5 4460 and H81 motherboards are affordable, you would benefit from the platform improvements that would come with a Skylake based system and perhaps an i5 6500 or something like that.
If you are set on the i5 4460 I suggest going with a B85 board for the PCIE 3.0 X16 slot which will extend the life of the machine as GPUs become more and more powerful.
Upgrading to skylake gives you access to DDR4, U.2, M.2 and other features that, while they can be found on socket 1150 boards, are much more common on 1151 including on lower end boards.
A lot of people buy a motherboard without paying attention to other features on the board. Do you need legacy support in the form of onboard VGA out or maybe PCI slots? Do you want high quality integrated audio? Are you ok with a low end NIC or would you prefer a higher end NIC? Does the board support Xfire/SLI? etc etc.
The motherboard is the most critical system component, because it is the component across which all other parts (excluding power supply) communicate with each other.