Firstly, his dual 680's are more powerful than your 7990, so he will get better performance regardless, though how much will vary from game to game.
Secondly, Physx is a technology for doing advanced physics on the GPU rather than CPU, but only in games that support it. You can enable it but like has been mentioned, it will cripple your CPU because it is not designed for the Physx code to be run on it and to run all of the game calculations as well.
Note that it is only in games that support it. Very few games do support it, and those that do it really isn't something to write home about. It is cloth moving more fluidly and extra particles on explosions, it isn't some massive difference that is hugely noticeable between Physx enabled and disabled, it is all little things.
Either disable it and you will not see the difference unless you know what to look for, or (and this would be silly imho) swap in your 7990 for whatever Nvidia equivalent you can then afford. It would be a waste of time and money to do this though because so few games support it and those that do have very little difference with or without it