I've run both NVidia and ATI models with MSI as the brand name of the card on more then one build. In fact I'm still going with an MSI card on the new build here. Never seen one ounce of problems with that brand of card regardless of who made the vpu chip. And yes I've also compared core and memory clocks on MSI to Asus, Sapphire, BFG, EVGA along with others to see theirs with the fastest at times. Asus amd EVGA also compete closely at second place often along with BFG and Sapphire.