NopeWould it matter much which one's primary master and primary slave?
How does it matter?it does if you are running an os off the 160. then primary master on that and slave on the 250.
Primary and secondary dont matter .... its prolly more effective to make the OS on the 10K drive (yes its a technicality but a someone significant one )I would only say it mattered depending upon the hard drive's speed... if one spins at 10,000 RPM and another at 5,400RPM then I'd say make the 10k RPM the primary